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Table 6 Five-year survival and crude and adjusted hazard ratios by sociodemograhic and clinical factors (n = 3,297).

From: Factors associated with initial treatment and survival for clinically localized prostate cancer: results from the CDC-NPCR Patterns of Care Study (PoC1)

Characteristic

5 yr Survival1(%)

Crude Hazard Ratio (95% CI)2

Adjusted3Hazard Ratio (95% CI)

Age at diagnosis

     

   <60

95.06

1.00

(referent)

1.00

(referent)

   60-64

93.38

1.38

(0.86 - 2.20)

1.28

(0.80 - 2.04)

   65-69

87.92

2.59

(1.73 - 3.89)

2.10

(1.39 - 3.18)

   70-74

85.60

3.33

(2.24 - 4.95)

2.28

(1.51 - 3.46)

   75-79

74.67

6.18

(4.18 - 9.14)

3.67

(2.41 - 5.60)

   >= 80

50.82

13.00

(8.78 - 19.25)

5.29

(3.43 - 8.16)

Race/ethnicity

     

   Non-Hispanic White

85.42

1.00

(referent)

1.00

(referent)

   Non-Hispanic Black

78.78

1.47

(1.18 - 1.83)

1.17

(0.92 - 1.48)

   Non-Hispanic Other

94.51

0.31

(0.10 - 0.95)

0.35

(0.11 - 1.10)

   Hispanic

92.65

0.51

(0.27 - 0.96)

0.53

(0.28 - 1.00)

   Unknown

78.25

1.40

(0.52 - 3.74)

1.29

(0.46 - 3.61)

Marital status

     

   Married

86.36

1.00

(referent)

1.00

(referent)

   Not Married

78.58

1.69

(1.40 - 2.05)

1.21

(1.00 - 1.48)

   Unknown

86.39

0.90

(0.59 - 1.35)

0.67

(0.43 - 1.03)

Registry

     

   California

86.03

1.00

(referent)

1.00

(referent)

   Colorado

89.97

0.79

(0.56 - 1.10)

0.94

(0.66 - 1.33)

   Illinois

82.36

1.35

(1.00 - 1.82)

1.01

(0.74 - 1.38)

   Louisiana

78.80

1.69

(1.28 - 2.25)

1.37

(1.02 - 1.84)

   New York

86.90

1.01

(0.73 - 1.40)

1.10

(0.78 - 1.54)

   Rhode Island

88.38

0.91

(0.65 - 1.27)

0.82

(0.58 - 1.16)

   South Carolina

79.79

1.72

(1.21 - 2.44)

1.54

(1.06 - 2.24)

PSA value

     

   0-4

90.49

1.00

(referent)

1.00

(referent)

   >4-10

89.28

1.00

(0.69 - 1.44)

1.07

(0.73 - 1.55)

   >10-20

84.65

1.50

(1.01 - 2.21)

1.20

(0.81 - 1.79)

   20+

75.77

2.43

(1.64 - 3.60)

1.38

(0.92 - 2.09)

   Unknown

73.16

2.65

(1.80 - 3.90)

1.82

(1.22 - 2.70)

Gleason score

     

   2-4

83.90

1.00

(referent)

1.00

(referent)

   5-7

86.73

1.10

(0.81 - 1.50)

1.35

(0.98 - 1.85)

   8-10

73.69

2.21

(1.54 - 3.19)

1.96

(1.34 - 2.86)

   Unknown

74.52

2.29

(1.55 - 3.38)

1.69

(1.13 - 2.51)

Treatment

     

   Radical prostatectomy

93.68

1.00

(referent)

1.00

(referent)

   Radiation therapy

85.99

2.55

(1.97 - 3.31)

1.66

(1.24 - 2.21)

   Hormonal therapy

65.24

6.75

(5.13 - 8.88)

2.83

(2.06 - 3.90)

   Watchful waiting

75.47

4.73

(3.65 - 6.14)

2.30

(1.70 - 3.12)

Comorbidity score4

     

   ≤1 year post diagnosis

     

   0

86.69#

1.00

(referent)

1.00

(referent)

   1

79.68#

2.84

(1.39 - 5.81)

2.16

(1.05 - 4.41)

   2+

62.62#

9.90

(4.78 - 20.88)

6.39

(3.04 - 13.42)

   >1 to 3 years post diagnosis

     

   0

 

1.00

(referent)

1.00

(referent)

   1

 

1.56

(1.08 - 2.26)

1.20

(0.83 - 1.74)

   2+

 

3.99

(2.52 - 6.31)

2.67

(1.68 - 4.25)

   >3 years post diagnosis

     

   0

 

1.00

(referent)

1.00

(referent)

   1

 

1.48

(1.09 - 2.00)

1.22

(0.90 - 1.66)

   2+

 

2.16

(1.30 - 3.58)

1.47

(0.88 - 2.45)

  1. 1: 5-year survival following diagnosis conditional on having survived the first six months following diagnosis.
  2. 2: OR = odds ratio; CI = confidence interval.
  3. 3: Adjusted for factors shown in the table.
  4. 4: Hazard associated with comorbidity is time dependent.
  5. #: 5 year survival percent (not stratified by time since diagnosis)