Skip to main content

Table 3 The estimates of population genetic parameters (p, u, v) and quantitative genetic parameters (a, d, d', λ, I aλ , I dλ , I d'λ ) from simulated data with different sample size and heritability combinations.

From: Modeling the Aneuploidy Control of Cancer

Sample Size

H 2

p

u

v

a

d

d '

λ

I aλ

I dλ

I d'λ

True Value

 

0:6

0:3

0:4

0:8

0:5

0:4

0:5

0:4

0:5

0:3

400

0.05

0:5973

0:2974

0:3389

0:9378

0:7793

0:5928

0:7974

0:6869

0:9731

0:5860

  

(0:0017)

(0:0149)

(0:0197)

(0:0468)

(0:1618)

(0:1052)

(0:0832)

(0:0590)

(0:2354)

(0:1218)

 

0.1

0:6014

0:2803

0:3783

0:9252

0:5270

0:3571

0:6732

0:5647

0:6423

0:5066

  

(0:0016)

(0:0183)

(0:0190)

(0:0404)

(0:1548)

(0:0662)

(0:0664)

(0:0447)

(0:1854)

(0:0750)

 

0.2

0:6016

0:2873

0:4139

0:8333

0:5436

0:3354

0:5116

0:4308

0:4066

0:3433

  

(0:0016)

(0:0161)

(0:0198)

(0:0274)

(0:0798)

(0:0554)

(0:0435)

(0:0294)

(0:1093)

(0:0481)

800

0.05

0:5980

0:2463

0:3449

1:0740

0:6989

0:3363

0:8930

0:7510

0:6963

0:5266

  

(0:0012)

(0:0154)

(0:0227)

(0:0576)

(0:2247)

(0:1128)

(0:0909)

(0:0626)

(0:2694)

(0:1153)

 

0.1

0:5993

0:2722

0:3783

0:8945

0:6552

0:4731

0:6004

0:5015

0:6375

0:5637

  

(0:0013)

(0:0156)

(0:0210)

(0:0349)

(0:1199)

(0:0854)

(0:0606)

(0:0399)

(0:1565)

(0:0781)

 

0.2

0:5988

0:2809

0:3763

0:8756

0:4041

0:4281

0:5925

0:4799

0:3461

0:3254

  

(0:0011)

(0:0166)

(0:0194)

(0:0275)

(0:0781)

(0:0444)

(0:0379)

(0:0253)

(0:1035)

(0:0466)

2000

0.05

0:6011

0:2428

0:3656

1:0367

0:7602

0:3605

0:7556

0:6271

0:8159

0:4858

  

(0:0007)

(0:0165)

(0:0209)

(0:0622)

(0:2001)

(0:0852)

(0:0995)

(0:0647)

(0:2416)

(0:1019)

 

0.1

0:6008

0:2812

0:3805

0:8417

0:6676

0:4135

0:4838

0:4217

0:6970

0:5141

  

(0:0007)

(0:0161)

(0:0211)

(0:0320)

(0:1337)

(0:0546)

(0:0537)

(0:0370)

(0:1585)

(0:0622)

 

0.2

0:6001

0:2860

0:3771

0:8103

0:5607

0:4490

0:4614

0:3758

0:6301

0:3942

  

(0:0008)

(0:0132)

(0:0185)

(0:0153)

(0:0511)

(0:0383)

(0:0297)

(0:0195)

(0:0699)

(0:0331)

  1. The numbers in parentheses are the sampling errors of the estimates.