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Table 1 Expression and distribution of angiogenic molecules in HCC tissue arrays

From: Mechanism of endothelial progenitor cell recruitment into neo-vessels in adjacent non-tumor tissues in hepatocellular carcinoma

 

HC

AT

HCC

 

(-)

(+)

(++)

Positive Percent

(-)

(+)

(++)

Positive Percent

(-)

(+)

(++)

Positive Percent

VEGF-A

35

3

6

20.5%

43

9

46

56.1%**

41

29

27

57.7%^^##

bFGF

27

4

13

38.6%

29

13

55

70.1%**

32

41

23

66.7%^^##

TGF-β

20

8

16

54.5%

11

4

83

88.8%**

14

15

68

85.6%^^#

MCP-1

20

8

8

44.4%

32

21

44

67.0%*

59

21

17

39.2%##

TSP-1

38

4

1

11.6%

43

14

41

56.1%**

37

33

27

61.9%^^##

MMP-9

28

7

9

36.4%

25

13

59

74.2%**

40

23

35

59.2%^##

TIMP-1

24

2

13

38.5%

63

14

17

33.0%

69

10

17

28.1%

TIMP-2

21

6

17

52.3%

19

13

66

80.6%**

26

37

35

73.5%^^##

Endostatin

23

9

10

45.2%

14

9

75

85.7%**

37

21

40

62.2%##

COX-2

25

9

10

43.2%

7

39

51

92.8%**

9

46

43

90.8%^^

NOS-2

32

9

3

27.3%

37

21

40

62.2%**

43

30

25

56.1%^^

  1. *p < 0.05, **p < 0.01, AT versus HC; # p < 0.05, ## p < 0.01, HCC versus AT, ^p < 0.05; ^^p < 0.01, HCC versus HC