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Figure 1 | BMC Cancer

Figure 1

From: MRP3: a molecular target for human glioblastoma multiforme immunotherapy.

Figure 1

Structure of MRP3 and expression of MRP3 mRNA in glioblastoma-derived cell lines. (A) MRP3 structure. Upper: the organization of MRP3. Lower: membrane topology model for MRP3 (modified from Hipfner et al. [40]). MAR1, MAR2, MAR3, membrane-associated regions 1-3; L1, L2, linker domains 1 and 2; NBD1, NBD2, nucleotide-binding domains 1 and 2. Positions of PCR primers are indicated by arrows. (B) RT-PCR results showing MRP3 mRNA expression (Upper) and β-actin expression (Lower) in GBM cell lines U251 MG, T98G, D245 MG, D54 MG, D247 MG, and D392 MG.

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