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Figure 2 | BMC Cancer

Figure 2

From: Promoter methylation and large intragenic rearrangements of DPYD are not implicated in severe toxicity to 5-fluorouracil-based chemotherapy in gastrointestinal cancer patients

Figure 2

Illustrative QMSP amplification plots for 4 serial 10×-dilutions of fully methylated, bisulfite converted DNA (A, B, C, D) and DPYD promoter methylation in RKO cell line (*). The DPYD/ACTB ratios were determined using the cycle number where fluorescence per reaction crossed the threshold, which is set to the geometrical phase of polymerase chain reaction amplification above background. ΔRn is defined as the cycle-to-cycle change in the fluorescence signal (log scale).

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BMC Cancer

ISSN: 1471-2407

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