Table 2 GO enrichment analysis of genes that correlated to the quantified metabolites, using GOrilla.
From: Merging transcriptomics and metabolomics - advances in breast cancer profiling
Metabolite/GO-category | GO-Term | Description | P-value | Enrichment | (N,B,n,b) |
|---|---|---|---|---|---|
myo-Inositol | |||||
BP | GO:0032502 | developmental process | 6.40E-10 | 1.45 | (7307,1397,864,240) |
BP | GO:0030198 | extracellular matrix organization | 1.00E-09 | 7.16 | (7307,56,310,17) |
BP | GO:0007155 | cell adhesion | 1.20E-08 | 2.45 | (7307,377,412,52) |
BP | GO:0022610 | biological adhesion | 1.40E-08 | 2.44 | (7307,378,412,52) |
BP | GO:0043062 | extracellular structure organization | 2.20E-07 | 4.92 | (7307,86,311,18) |
MF | GO:0005201 | extracellular matrix structural constituent | 2.10E-09 | 7.39 | (7307,51,310,16) |
CC | GO:0005576 | extracellular region | 3.80E-21 | 2.76 | (7307,885,311,104) |
CC | GO:0044421 | extracellular region part | 7.10E-17 | 2.28 | (7307,513,757,121) |
CC | GO:0031012 | extracellular matrix | 5.30E-15 | 5.34 | (7307,159,310,36) |
CC | GO:0005578 | proteinaceous extracellular matrix | 2.90E-14 | 5.57 | (7307,142,305,33) |
CC | GO:0044420 | extracellular matrix part | 2.30E-10 | 3.44 | (7307,71,986,33) |
CC | GO:0005581 | collagen | 1.60E-08 | 21.83 | (7307,26,103,8) |
Taurine | |||||
BP | GO:0032502 | developmental process | 8.20E-08 | 1.48 | (7307,1397,630,178) |
BP | GO:0048731 | system development | 1.90E-07 | 2.23 | (7307,314,554,53) |
MF | GO:0005201 | extracellular matrix structural constituent | 6.20E-10 | 16.25 | (7307,51,97,11) |
CC | GO:0044421 | extracellular region part | 8.30E-14 | 2.44 | (7307,513,485,83) |
CC | GO:0005576 | extracellular region | 3.90E-12 | 2.35 | (7307,885,267,76) |
CC | GO:0031012 | extracellular matrix | 2.60E-10 | 3.43 | (7307,159,482,36) |
CC | GO:0044420 | extracellular matrix part | 1.80E-09 | 12.73 | (7307,71,97,12) |
CC | GO:0005578 | proteinaceous extracellular matrix | 2.10E-09 | 3.52 | (7307,142,482,33) |
CC | GO:0005581 | collagen | 5.10E-08 | 9.48 | (7307,26,326,11) |
Choline | |||||
BP | GO:0090304 | nucleic acid metabolic process | 2.00E-09 | 1.75 | (7307,497,990,118) |
BP | GO:0022402 | cell cycle process | 2.30E-08 | 2.09 | (7307,239,952,65) |
BP | GO:0007059 | chromosome segregation | 3.90E-07 | 4.65 | (7307,25,943,15) |
BP | GO:0006139 | nucleobase, nucleoside, nucleotide and nucleic acid metabolic process | 8.80E-07 | 1.54 | (7307,640,994,134) |
CC | GO:0044428 | nuclear part | 9.80E-11 | 1.7 | (7307,632,999,147) |
CC | GO:0005634 | nucleus | 5.80E-09 | 1.3 | (7307,2062,990,364) |
CC | GO:0000775 | chromosome, centromeric region | 2.50E-08 | 10.2 | (7307,26,303,11) |
Glucose | |||||
BP | GO:0002376 | immune system process | 1.60E-09 | 1.83 | (7307,420,999,105) |
Creatine | |||||
MF | GO:0000030 | mannosyltransferase activity | 5.80E-08 | 73.81 | (7307,4,99,4) |
Glycine | |||||
CC | GO:0070469 | respiratory chain | 5.80E-07 | 4.74 | (7307,22,981,14) |