| Entire Cohort | Evaluated Cohort | Evaluated Cohort | ||||||
---|---|---|---|---|---|---|---|---|---|
 | (n = 512) | (n = 359) | (n = 359) | ||||||
 | Known | Unknown | p value | SNAS < 4.26 | SNAS > 4.26 | p value | CNR < 5 | CNR > 5 | p value |
 | (n = 359) | (n = 153) |  | (n = 201) | (n = 158) |  | (n = 198) | (n = 161) |  |
Age (Years) | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Median (Range) | Â | Â | Â | Â | Â | Â | Â | Â | Â |
< median (25-65) | 53(49.1) | 175(48.7) | 0.520 | 98(48.8) | 77(48.7) | 0.541 | 99(50) | 76(47.2) | 0.598 |
> median (65-96) | 55(50.9) | 184(51.3) | Â | 103(51.2) | 81(51.3) | Â | 99(50) | 85(52.8) | Â |
Tumour Size | Â | Â | Â | Â | Â | Â | Â | Â | Â |
0 - 20 mm | 255(71.6) | 84(79.2) | 0.119 | 148(73.6) | 107(69) | 0.340 | 134 (68.7) | 121(75.2) | 0.180 |
> 21 mm | 101(28.4) | 22(20.8) | Â | 53(26.4) | 48(31) | Â | 61(31.3) | 40(24.8) | Â |
Unknown | 3 | Â | Â | 3 | Â | Â | 3 | Â | Â |
Nodal status | Â | Â | Â | Â | Â | Â | Â | Â | Â |
N0 | 203(63.6) | 66(67.3) | 0.502 | 110(62.1) | 93(65.5) | 0.537 | 118(65.9) | 85(60.1) | 0.337 |
N1+ | 116(36.4) | 32(32.7) | Â | 67(37.9) | 49(34.5) | Â | 61(34.1) | 55(39.2) | Â |
Unknown | 40 | Â | Â | 19 | Â | Â | 19 | Â | Â |
NHG | Â | Â | Â | Â | Â | Â | Â | Â | Â |
I&II | 237(66.2) | 73(67.6) | 0.788 | 145(72.5) | 92(58.2) | 0.005 | 119(60.1) | 118(73.7) | 0.007 |
III | 121(33.8) | 35(32.4) | Â | 55(27.5) | 66(41.8) | Â | 79(39.9) | 42(26.2) | Â |
Unknown | 1 | Â | Â | Â | Â | Â | Â | Â | Â |
ER status | Â | Â | Â | Â | Â | Â | Â | Â | Â |
ER <10% | 81(22.9) | 25(23.8) | 0.843 | 40(20.2) | 41(26.3) | 0.176 | 53(27.1) | 28(17.7) | 0.038 |
ER >10% | 273(77.1) | 80(76.2) | Â | 158(79.8) | 115(73.7) | Â | 143(72.9) | 130(82.3) | Â |
Unknown | 5 | Â | Â | 2 | Â | Â | 2 | Â | Â |
PR Status | Â | Â | Â | Â | Â | Â | Â | Â | Â |
PR <10% | 151(42.7) | 50(47.6) | 0.368 | 82(41.4) | 69(44.2) | 0.595 | 89 (45.4) | 62(39.2) | 0.243 |
PR >10% | 203(57.3) | 55(52.4) | Â | 116(58.6) | 87(55.8) | Â | 107(54.6) | 96(60.8) | Â |
Unknown | 5 | Â | Â | 2 | Â | Â | 2 | Â | Â |
Ki-67 | Â | Â | Â | Â | Â | Â | Â | Â | Â |
< 10% | 128(27.8) | 35(37.2) | 0.926 | 82(43.9) | 46(30.3) | 0.010 | 55(29.2) | 73(48.3) | <0.001 |
> 10% | 211(62.2) | 59(62.8) | Â | 105(56.1) | 106(69.7) | Â | 133(70.7) | 78(51.6) | Â |
Unknown | 20 | Â | Â | 10 | Â | Â | 10 | Â | Â |
Her2 IHC | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Normal/weak (0 - 2+) | 285(80.5) | 81(77.1) | 0.451 | 166(83.9) | 119(76.3) | 0.075 | 149(76.1) | 136(86.1) | 0.018 |
Overexpressed (3+) | 69(19.5) | 24(22.9) | Â | 32(16.1) | 37(23.7) | Â | 47(23.9) | 22(13.9) | Â |
Unknown | 5 | Â | Â | 2 | Â | Â | 2 | Â | Â |