Skip to main content

Table 2 Multivariate Cox model for overall survival (OS) and desease-free survival (DFS)

From: Weight change during chemotherapy changes the prognosis in non metastatic breast cancer for the worse

Category

OS

DFS

 

e/n

RR

95% - CI

P

e/n

RR

95% - CI

P

Weight variation

   

0.0082*

   

0.0046*

   < 5% (reference)

36/77

1.00

  

34/77

1.00

  

   > 5%

21/34

2.11

1.21 - 3.66

 

21/34

2.28

1.29 - 4.03

 

Clinical Node Involement

   

0.054

   

0.021*

   N0 (reference)

22/55

1.00

  

23/55

1.00

  

   N1

30/49

1.61

0.99 - 2.61

 

27/49

1.78

1.09 - 2.91

 

   N2

4/6

2.59

0.98 - 6.80

 

4/6

3.18

1.19 - 8.49

 

   N3

1/1

4.16

0.99 - 16.40

 

1/1

5.66

1.29 - 24.76

 

Tumor stage

   

0.084

   

0.14

   T1 (reference)

6/21

1.00

  

7/21

1.00

  

   T2

24/49

1.32

0.96 - 1.81

 

25/49

1.17

0.85 - 1.60

 

   T3

10/17

1.74

0.93 - 3.27

 

7/17

1.37

0.73 - 2.57

 

   T4

17/24

2.30

0.90 - 5.90

 

16/24

1.60

0.60 - 4.13

 

Initial BMI

   

0.20

   

0.33

   < 24 kg/m2

21/52

1.00

  

21/52

1.00

  

   ≥ 24 kg/m2

36/59

1.49

0.81 - 2.74

 

34/59

1.59

0.86 - 2.93

 

Menopausal status

   

0.79

   

0.46

   Premenopausal (reference)

21/50

1.00

  

23/50

1.00

  

   Menopausal

36/61

1.09

0.59 - 1.99

 

32/61

0.96

0.53 - 1.76

 

Hormonotherapy

   

0.81

   

0.90

   no (reference)

34/67

1.00

  

36/67

1.00

  

   yes

23/44

0.93

0.53 - 1.65

 

19/14

0.80

0.44 - 1.14

 
  1. * P value considered statistically significant (p < 0.05).
  2. All the variable in the table were mutually adjusted for each other.