Figure 1From: Mutually exclusive expression of DLX2 and DLX5/6 is associated with the metastatic potential of the human breast cancer cell line MDA-MB-231 Expression of DLX2 , DLX5 and DLX6 in MDA-MB231 cells in vitro and in vivo. The pattern of expression of DLX2, 5 and 6 in cultured MDA-MB-231 cells paralleled that observed in nodules resulting from subcutaneous injection into nude mice: a strong DLX2 expression was found, while neither DLX5 nor DLX6 were present. Lung metastases generated by injection of MDA-MB-231 into the left cardiac ventricle of nude mice displayed the opposite pattern of expression, with undetectable levels of DLX2 and high levels of DLX5 and 6.Back to article page