Clinical factors | rtA181T | OR (95%CI) | P Value | |
---|---|---|---|---|
 | Yes (n = 10) | No (n = 113) |  |  |
Sex (male) | 10 (100%) | 91 (80.5%) | > 106 (0-> 106) | 0.998 |
Age (years) | 58.5 ± 8.3 | 45.7 ± 10.1 | 1.144 (1.056-1.240) | 0.001a |
rtM204V | 2 (20.0%) | 42 (37.2%) | 1.582 (0.423-5.909) | 0.495 |
rtM204I | 4 (40.0%) | 58 (51.3%) | 2.366 (0.480-11.670) | 0.290 |
rtM204V+I | 4 (40.0%) | 13 (11.5%) | 5.128 (1.276-20.607) | 0.021 |
rtL180M | 3 (30.0%) | 31 (27.4%) | 1.134 (0.276-4.663) | 0.862 |
HBeAg | 2 (20.0%) | 63 (55.8%) | 0.198 (0.040-0.976) | 0.047 |
HBV-DNA (106 copies/mL) | 15 (0.0015-16063) | 2.08 (0.001-4640) | 1.000 (0.999-1.001) | 0.688 |
AST (IU/L) | 147.0 ± 220.2 | 114.1 ± 122.1 | 0.999 (0.996-1.003) | 0.693 |
ALT (IU/L) | 217.3 ± 335.9 | 124.7 ± 124.7 | 0.999 (0.995-1.002) | 0.408 |
Alpha-fetoprotein (ng/dL) | 3 (0-18) | 4 (0-17) | 0.998 (0.997-1.001) | 0.876 |
BCP mutation | 7 (70.0%) | 52 (46.0%) | 2.737 (0.674-11.124) | 0.159 |
Precore stop codon mutation | 4 (40.0%) | 52 (46.0%) | 0.782 (0.209-2.922) | 0.715 |
Genotype C | 4 (40.0%) | 35 (31.0%) | 1.486 (0.394-5.598) | 0.559 |
Pre-S internal deletions | 3 (30.0%) | 29 (25.7%) | 2.024 (0.532-7.693) | 0.301 |
Cirrhosis | 8 (80.0%) | 32 (28.3%) | 10.125 (2.039-50.281) | 0.005 |
Duration of LAM treatment (months) | 13 (6-55) | 13.5 (6-48) | 1.043 (0.990-1.099) | 0.117 |