Table 1 HSD17B1 transcript and protein levels in primary cancerous and histopathologically unchanged tissue samples from patient with CRC.

Age (Years)

<60

10

3.511 (2.109-3.868) ^a

3.282 ± 0.5921 ^a

3.415 (2.726-5.107)^a

3.611 ± 0.6309 ^a

0.2450^a

2.634 (1.681-3.218)^b

2.579 ± 0.5243^b

2.620 (2.108-3.398)^b

2.719 ± 0.4843^b

0.5423^b

>60

42

3.531 (2.071-5.227) ^a

3.569 ± 0.6649 ^a

3.692 (2.790-5.785)^a

3.834 ± 0.6251^a

0.1087^a

2.728 (1.728-4.023)^b

2.720 ± 0.4702^b

2.952 (1.364-3.472)^b

2.835 ± 0.4913^b

0.1121^b

Gender

Female

20

3.384 (2.109-4.455) ^a

3.371 ± 0.5676 ^a

3.449 (2.726-5.785)^a

3.719 ± 0.7333^a

0.2340 ^a

2.793 (1.681-3.218)^b

2.666 ± 0.4767^b

2.811 (2.108-3.472)^b

2.844 ± 0.4065^b

0.2119^b

Male

32

3.571 (2.071-4.653) ^a

3.557 ± 0.6523 ^a

3.857(2.790-5.259) ^a

3.890 ± 0.5855 ^a

0.0388 ^a

2.702 (1.728-4.023)^b

2.713 ± 0.4941^b

2.962 (1.364-3.449)^b

2.792 ± 0.5395^b

0.2832^b

CRC localization

Proximal colon (cecum to transverse)

20

3.507(2.666-4.455) ^a

3.427 ± 0.4350 ^a

3.874 (3.050-5.785) ^a

4.057 ± 0.7488 ^a

0.0016 ^a

2.793 (1.681-3.218)^b

2.666 ± 0.4767^b

2.811 (2.108-3.472)^b

2.844 ± 0.4065^b

0.0028^b

Distal colon (splenic flexture to sigmoid)

12

3.214 (2.071-4.313) ^a

3.218 ± 0.7760 ^a

3.449 (2.726-4.587) ^a

3.630 ± 0.6372 ^a

0.1685 ^a

2.798 (1.772-3.254)^b

2.691 ± 0.4777^b

2.860 (1.364-3.391)^b

2.619 ± 0.6350^b

0.7763^b

Rectum

20

3.544 (2.523-4.653) ^a

3.657 ± 0.6011 ^a

3.564 (3.226-4.862) ^a

3.762 ± 0.500 ^a

0.8839 ^a

2.951 (1.728-3.398)^b

2.815 ± 0.4436^b

2.988 (2.019-3.383)^b

2.913 ± 0.3871^b

0.5019^b

Histologic grade

G1

4

4.059 (2.362-4.402) ^a

3.721 ± 0.9467 ^a

4.431 (3.123-5.259) ^a

4.311 ± 0.9076 ^a

0.4026 ^a

2.926 (2.586-3.040)^b

2.870 ± 0.2060^b

2.789 (2.026-3.147)^b

2.688 ± 0.5370^b

0.5506^b

G2

35

3.379 (2.109-4.621) ^a

3.363 ± 0.5385 ^a

3.524 (2.726-5.785) ^a

3.681 ± 0.5619 ^a

0.0335 ^a

2.647 (1.681-4.023)^b

2.649 ± 0.4993^b

2.933 (2.019-3.472)^b

2.863 ± 0.4114^b

0.0659^b

G3

13

3.875 (2.071-4.839) ^a

3.807 ± 0.7092 ^a

4.043 (2.790-5.227) ^a

4.165 ± 0.7346 ^a

0.2587 ^a

2.676 (1.845-3.431)^b

2.670 ± 0.5098^b

3.023 (1.364-3.449)^b

2.763 ± 0.6858^b

0.5114^b