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Table 2 Associations of measures of patterns of sunlight exposure in BCC and SCC cases and controls

From: Patterns and timing of sunlight exposure and risk of basal cell and squamous cell carcinomas of the skin – a case–control study

 

Controls (n = 316)

Basal cell carcinoma (n = 218)

Squamous cell carcinoma (n = 169)

Variable

n (%)

n (%)

OR (95% CI)1

OR (95% CI)2

n (%)

OR (95% CI)1

OR (95% CI)2

Blistering Sunburn

No

101 (32.3)

54 (25.0)

1.00 (reference)

1.00 (reference)

38 (23.0)

1.00 (reference)

1.00 (reference)

Yes

212 (67.7)

162 (75.0)

1.96 (1.27-3.03)

1.56 (0.96-2.54)

127 (77.0)

2.02 (1.22-3.33)

1.24 (0.71-2.18)

Job in sun ≥3 months

No

227 (72.8)

120 (55.3)

1.00 (reference)

1.00 (reference)

86 (51.8)

1.00 (reference)

1.00 (reference)

Yes

85 (27.2)

97 (44.7)

1.38 (0.89-2.14)

1.31 (0.81-2.12)

80 (48.2)

1.73 (1.06-2.83)

1.72 (0.99-2.97)

# years with job

       

≤10

57 (18.7)

47 (22.3)

1.17 (0.70-1.94)

1.07 (0.61-1.86)

44 (27.0)

1.64 (0.94-2.86)

1.64 (0.88-3.07)

>10

21 (6.9)

44 (20.9)

2.14 (1.12-4.11)

2.12 (1.05-4.27)

33 (20.2)

2.54 (1.23-5.28)

2.36 (1.07-5.20)

   

ptrend = 0.03

ptrend = 0.06

 

ptrend = 0.01

ptrend = 0.02

Lifetime tanning bed use

209 (71.3)

175 (82.5)

1.00 (reference)

1.00 (reference)

127 (80.9)

1.00 (reference)

1.00 (reference)

Never used

44 (15.0)

25 (11.8)

0.99 (0.56-1.76)

0.99 (0.53-1.82)

18 (11.5)

1.01 (0.52-1.98)

0.80 (0.38-1.71)

1–10 times

40 (13.7)

12 (5.7)

0.64 (0.30-1.36)

0.64 (0.30-1.36)

12 (7.6)

1.67 (0.75-3.73)

1.85 (0.74-4.62)

>10 times

  

ptrend = 0.32

ptrend = 0.20

 

ptrend = 0.29

ptrend = 0.40

Apply SPF3 ≥15

Always/often

124 (39.6)

82 (37.8)

1.00 (reference)

1.00 (reference)

53 (32.5)

1.00 (reference)

1.00 (reference)

Sometimes

98 (31.3)

59 (27.2)

0.79 (0.50-1.26)

0.87 (0.52-1.45)

56 (34.4)

0.83 (0.49-1.42)

0.86 (0.47-1.59)

Rarely/never

91 (29.1)

76 (35.0)

0.83 (0.52-1.32)

0.93 (0.56-1.54)

54 (33.1)

0.79 (0.46-1.36)

0.87 (0.48-1.60)

Cumulative sunlight exposure

Low

87 (32.3)

52 (27.4)

1.00 (reference)

1.00 (reference)

35 (22.7)

1.00 (reference)

1.00 (reference)

Medium

92 (34.2)

54 (28.4)

1.02 (0.61-1.69)

1.42 (0.81-2.50)

57 (37.0)

1.49 (0.84-2.64)

2.36 (1.22-4.57)

High

90 (33.5)

84 (44.2)

1.37 (0.83-2.27)

1.88 (1.07-3.31)

62 (40.3)

1.59 (0.88-2.87)

2.47 (1.25-4.91)

Intermittent sunlight exposure

Low

91 (33.8)

80 (42.1)

1.00 (reference)

1.00 (reference)

59 (38.3)

1.00 (reference)

1.00 (reference)

Medium

84 (31.2)

52 (27.4)

0.99 (0.60-1.64)

1.26 (0.72-2.22)

46 (29.9)

1.25 (0.71-2.20)

1.58 (0.83-3.00)

High

94 (34.9)

58 (30.5)

1.15 (0.70-1.88)

1.23 (0.72-2.10)

49 (31.8)

1.48 (0.85-2.58)

1.57 (0.83-2.94)

Patterns by age at exposure

Teens

<1 hour

18 (6.0)

12 (6.0)

1.00 (reference)

1.00 (reference)

4 (2.5)

1.00 (reference)

1.00 (reference)

Continuous hours

151 (50.0)

113 (56.8)

1.04 (0.45-2.41)

0.97 (0.38-2.48)

96 (60.4)

2.33 (0.69-7.90)

1.76 (0.48-6.47)

Intermittent hours

133 (44.0)

74 (37.2)

1.08 (0.46-2.54)

1.10 (0.42-2.83)

59 (37.1)

2.26 (0.66-7.78)

1.86 (0.50-6.94)

Twenties

<1 hour

34 (11.3)

18 (9.0)

1.00 (reference)

1.00 (reference)

11 (6.9)

1.00 (reference)

1.00 (reference)

Continuous hours

102 (33.9)

91 (45.5)

1.36 (0.68-2.71)

1.58 (0.75-3.36)

74 (46.5)

2.01 (0.86-4.67)

2.99 (1.19-7.48)

Intermittent hours

165 (54.8)

91 (45.5)

1.30 (0.66-2.56)

1.56 (0.74-3.26)

74 (46.5)

2.11 (0.92-4.88)

3.15 (1.27-7.83)

Thirties

<1 hour

60 (20.5)

27 (13.6)

1.00 (reference)

1.00 (reference)

18 (11.3)

1.00 (reference)

1.00 (reference)

Continuous hours

85 (29.0)

79 (39.9)

1.31 (0.72-2.40)

1.77 (0.90-3.49)

69 (43.4)

1.55 (0.77-3.10)

2.25 (1.02-4.94)

Intermittent hours

148 (50.5)

92 (46.5)

1.38 (0.79-2.41)

2.09 (1.11-3.93)

72 (45.3)

1.47 (0.76-2.85)

1.95 (0.92-4.12)

Past 10 years

<1 hour

63 (28.6)

52 (30.2)

1.00 (reference)

1.00 (reference)

49 (33.1)

1.00 (reference)

1.00 (reference)

Continuous hours

74 (33.6)

83 (48.3)

0.88 (0.51-1.52)

1.14 (0.62-2.12)

64 (43.2)

0.81 (0.46-1.42)

1.35 (0.69-2.64)

Intermittent hours

83 (37.7)

37 (21.5)

0.57 (0.32-1.03)

0.67 (0.35-1.28)

35 (23.6)

0.60 (0.33-1.10)

0.93 (0.46-1.89)

  1. 1Odds ratios (OR) and 95% confidence intervals (CI) adjusted for age, gender, education, and history of ever smoking.
  2. 2OR and 95% CI adjusted for age, gender, education, history of ever smoking, ethnicity, eye and hair color, cutaneous sensitivity and tanning ability to sunlight exposure.
  3. 3SPF = sun protection factor.