Alcohol category | No. of cases | Person-years | Incidence rate/10,000 person-years | HR (95% CI)a | HR (95% CI)b |
---|---|---|---|---|---|
Follow-up from 1978 through 2008 | |||||
Frequency | Â | Â | Â | Â | Â |
Non-drinkers | 11 | 10,761 | 10.2 | 0.95 (0.47–1.92) | 0.96 (0.47– 1.93) |
A few times per year | 27 | 24,948 | 10.8 | 1 (reference) | 1 (reference) |
1–4 times per month | 132 | 94,719 | 13.9 | 1.37 (0.90–2.08) | 1.27 (0.83–1.94) |
2–7 times per week | 15 | 6,759 | 22.2 | 2.19 (1.16–4.13) | 2.00 (1.04–3.82) |
p-trend c | Â | Â | Â | Â | 0.11 |
Ethanol intake | Â | Â | Â | Â | Â |
Non-drinkers | 11 | 10,761 | 10.2 | 0.94 (0.47–1.89) | 0.95 (0.47–1.90) |
0.1–9.9 g/week | 29 | 26,574 | 10.9 | 1 (reference) | 1 (reference) |
10.0–24.9 g/week | 56 | 48,660 | 11.5 | 1.10 (0.70–1.72) | 1.04 (0.66–1.64) |
25.0–99.9 g/week | 56 | 34,858 | 16.1 | 1.57 (1.00–2.46) | 1.44 (0.91–2.29) |
≥100.0 g/week | 33 | 16,334 | 20.2 | 2.07 (1.26–3.42) | 1.90 (1.13–3.18) |
Continuous, per 1 SD (90 g/week)c |  |  |  |  | 1.12 (1.00–1.25) |
Follow-up from 1993 through 2008 | |||||
Frequency | Â | Â | Â | Â | Â |
Non-drinkers | 7 | 9,676 | 7.2 | 1.32 (0.52–3.30) | 1.34 (0.53–3.36) |
A few times per year | 13 | 23,282 | 5.6 | 1 (reference) | 1 (reference) |
1–4 times per month | 79 | 86,369 | 9.2 | 1.88 (1.04–3.39) | 1.81 (1.00–3.29) |
2–7 times per week | 11 | 5,917 | 18.6 | 3.95 (1.76–8.84) | 3.99 (1.75–9.11) |
p-trend c | Â | Â | Â | Â | 0.007 |
Ethanol intake | Â | Â | Â | Â | Â |
Non-drinkers | 7 | 9,676 | 7.2 | 1.20 (0.49–2.95) | 1.23 (0.50–3.01) |
0.1–9.9 g/week | 15 | 24,707 | 6.1 | 1 (reference) | 1 (reference) |
10.0–24.9 g/week | 32 | 44,576 | 7.2 | 1.32 (0.71–2.44) | 1.29 (0.69–2.39) |
25.0–99.9 g/week | 36 | 31,626 | 11.4 | 2.13 (1.16–3.88) | 2.06 (1.11–3.81) |
≥100.0 g/week | 20 | 14,658 | 13.6 | 2.74 (1.40–5.36) | 2.74 (1.37–5.49) |
Continuous, per 1 SD (90 g/week)c |  |  |  |  | 1.17 (1.03–1.32) |