Figure 3
From: Wnt5a promotes ewing sarcoma cell migration through upregulating CXCR4 expression
Promotion of ES cell migration by Wnt5a via CXCR4. (A) and (B) The number of migrated A-673 and RD-ES cells increased after treatment with rWnt5a, *P<0.01, vs Control. The increase was inhibited when these cells were pre-treated with CXCR4 antagonist AMD 3100, **P<0.01, vs rWnt5a. (C) and (D) The number of migrated SK-N-MC and SK-ES-1 cells decreased after transfection with Wnt5a shRNA, *P<0.01, vs Control and Control shRNA. Data are expressed as mean±SD, n=3.