Health-related quality of life in survivors of stage I-II breast cancer: randomized trial of post-operative conventional radiotherapy and hypofractionated tomotherapy

Table 6 Hypofractionated radiotherapy studies

Trial	Period	n	Hypofraction schedule	SIB	Mastectomy	Regional nodes	IMRT/ IGRT	Chemotherapy	Cosmesis	HRQOL
UK Start A [17, 19]	1998-2002	2236	3 Gy x 13 F/ 5 weeks	No	Yes	Yes	NS	Yes	Yes	Yes
UK Start A [17, 19]	1998-2002	2236	3.2 Gy x 13 F/ 5 weeks	No	Yes	Yes	NS	Yes	Yes	Yes
UK Start B [18, 19]	1999-2001	2215	2.67 Gy x 15 F/ 3 weeks	No	Yes	Yes	NS	Yes	Yes	Yes
Ontario [15]	1993-1996	1234	2.66 Gy x 16 F/ 3 weeks	No	No	No	NS	Yes	Yes	No
Egypt NCI [20]	2002-2003	30	2.66 Gy x 16 F/ 3 weeks	No	No	No	NS	No	Yes	No
UK FAST [21]	2004-2007	915	5.7 Gy x 5 F/ 5 weeks	?	No	No	Yes	No	No	No
UK FAST [21]	2004-2007	915	6 Gy x 5 F/ 5 weeks	?	No	No	Yes	No	No	No
Hopital Necker (*) [22]	1982-1984	230	5.75 Gy x 4 F/ 17 days	No	Yes	?	NS	Yes	No	No
Royal Marsden Hospital [23]	1986-1998	1410	3 Gy x 13 F/ 5 weeks 3.3 Gy x 13 F/ 5 weeks	No	No	Yes	NS	No	No	No
Lahore [24]	1998-2004	300	5.4 Gy x 5 F/ 1 week 3.5 Gy x 10 F/ 2 weeks	No	Yes	Yes	NS	Yes	No	No
Lahore [24]	1998-2004	300	2.66 Gy x 15 F/ 3 weeks	No	Yes	Yes	NS	Yes	No	No
UZ Brussel	2007-2011	121	2.8 Gy [SIB 3.4 Gy]x15 F/ 3 weeks	Yes	Yes	Yes	Yes	Yes	No	Yes