Response | Definition |
---|---|
Progressive metabolic disease | An increase in 18FDG tumor SUV of greater than 25% within the tumor region defined on the baseline scan, visible increase in the extent of 18FDG tumor uptake (>20% in the longest dimension) or the appearance of new 18FDG uptake in metastatic lesions |
Stable metabolic disease | An increase in tumor 18FDG SUV of less than 25% or a decrease of less than 15% and no visible increase in extent of 18FDG tumor uptake (>20% in the longest dimension) |
Partial metabolic response | A reduction of a minimum of 15–25% in tumor 18FDG SUV after one cycle of chemotherapy, and greater than 25% after more than one treatment cycle |
Complete metabolic response | Complete resolution of 18FDG uptake within the tumor volume so that it was indistinguishable from surrounding normal tissue |