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Table 2 Clinicopathologic features and level of TFPI-2 protein in the TFPI-2 positive group

From: Low expression of TFPI-2 associated with poor survival outcome in patients with breast cancer

 

Category

No. of cases

Meandensity of TFPI-2 Mean± SD

Statistics value

p value

Age

≤55

74

0.324±0.061

t=0.302

0.764

 

>55

47

0.327±0.052

  

Tumor size

≤2 cm

56

0.351±0.061

t=4.948

0.001

 

>2 cm

65

0.303±0.044

  

Skin involvementa

No

96

0.336±0.057

t=4.252

0.001

 

Yes

25

0.284±0.038

  

LN metastasis

0

70

0.348±0.055

F=12.896b

0.001

 

1-3

22

0.292±0.043

  
 

4-9

15

0.316±0.048

  
 

10-

13

0.272±0.038

  
 

Unknown

1

   

Histologic grade

≤II

71

0.339±0.057

t=3.389

0.001

 

>II

50

0.305±0.052

  

Vessel invasion

Absence

109

0.333±0.054

t=5.172

0.001

 

Presence

12

0.251±0.030

  

Clinical stagec

I

35

0.375±0.053

Chi-Square=43.867c

0.001

 

II

52

0.317±0.048

  
 

III

34

0.286±0.034

  

ER

(-)

43

0.327±0.055

t=0.253

0.801

 

(+)

77

0.324±0.059

  
 

Unknown

1

   

PR

(-)

63

0.319±0.055

t=-1.211

0.228

 

(+)

57

0.332±0.060

  
 

Unknown

1

   

HER-2

(-)

62

0.333±0.059

t=1.361

0.176

 

(+)

55

0.318±0.056

  
 

Unknown

4

   

Tumor type

IDCd

98

0.324±0.057

t=0.488

0.626

 

Non-IDCe

23

0.330±0.059

  
  1. a skin involvement include: edema, redness, nodularity, or ulceration of the skin.
  2. b Post Hoc Multiple Comparisons(LSD) shows difference of TFPI-2 expression is only present in the group without LN metastasis and the other groups.
  3. c Post Hoc Multiple Comparisons(Games-Howell) shows difference of TFPI-2 expression was significant among the groups (Nonparametric Test).
  4. d IDC, invasive ductal carcinoma.
  5. e Non-IDC include: invasive lobular carcinoma, mucinous or colloid carcinoma, medullary carcinoma, metaplastic carcinoma.