Figure 2From: Genetic variations of the A13/A14 repeat located within the EGFR3′ untranslated region have no oncogenic effect in patients with colorectal cancer Detection of EGFR 3′UTR polyA tract somatic mutations, using fluorescent multiplex PCR. The profile generated from malignant tissue (red) was superimposed on that obtained from distant non-malignant tissue (blue) after alignment of the control amplicons (peaks to the right corresponding to PCBD2). A: Pattern observed in a non mutated sample with A13/A14 genotype. B: Pattern observed in a mutated sample with A13/A14 genotype; notice in the tumor sample a shift of the peaks to the left corresponding to A11 and A12 repeats.Back to article page