Table 4 Representative genes differentially expressed between HCC recurrence and non-recurrence groups

Up-regulated genes in the recurrence group

          Angiogenesis related

0.0001

-5.19

Platelet derived growth factor C

PDGFC

AI446155

0.0006

-4.37

Sperm equatorial segment protein 1

NOX5

NM_145658

0.0010

-4.13

Interleukin 18

IL18

AI800476

          Cancer stem cell related

0.0004

-4.63

Prominin 1

PROM1

NM_006017

0.0018

-3.83

Pyruvate kinase, muscle

PKM2

NM_002654

          Positive regulator of Wnt

0.0018

-3.84

TGFB-induced factor (TALE family homeobox)

TGIF1

AI866302

0.0018

-3.84

NK2 transcription factor related, locus 5

NKX2-5

NM_004387

          Tumor progression related

0.0005

-4.47

Transcriptional co-activator with PDZ-binding motif

WWTR1

AK025216

0.0017

-3.87

Roundabout, axon guidance receptor, homolog 1

ROBO1

NM_133631

0.0018

-3.84

Hepatitis B virus x associated protein

RSF1

NM_016578

0.0019

-3.79

Heat shock 27kDa protein 2

HSPB2

NM_001541

Up-regulated genes in the non-recurrence group

Liver function and hepatocytes differenti related

0.0002

4.88

Metallothionein 2A

MT2A

NM_005953

0.0002

4.08

CCAAT/enhancer binding protein (C/EBP), alpha

CEBPA

NM_004364

0.0003

4.72

Forkhead box A3

FOXA3

NM_004497

0.0006

4.42

Hemopexin

HPX

NM_000613

0.0006

4.35

Metallothionein 1H

MT1H

NM_005951

0.0013

4.01

Forkhead box A1

FOXA1

NM_004496

0.0014

3.97

FK506 binding protein 8, 38kDa

FKBP8

NM_012181

Tumor suppressor related

0.0005

4.51

Deleted in colorectal carcinoma

DCC

X76132

0.0018

3.84

NK3 transcription factor related, locus 1

NKX3-1

NM_006167

Apoptosis inducing

0.0015

3.93

BH3 interacting domain death agonist

BID

NM_197967

0.0019

3.82

Programmed cell death 8

AIFM1

NM_145813