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Table 2 Univariate and multivariate analysis for relapse-free survival (Cox’s proportional hazards model)

From: A comprehensive analysis of Aurora A; transcript levels are the most reliable in association with proliferation and prognosis in breast cancer

Variable

Univariate analysis

Multivariate analysis

 

HR

95% CI

P

HR

95% CI

P

Age

1.03

0.46–2.59

0.95

   

Menopausal status

0.89

0.42–2.04

0.77

   

Tumor size

2.97

1.35–7.46

0.006

2.51

1.05–6.95

0.037

Nodal status

2.07

1.02–4.31

0.044

1.81

0.86–3.96

0.12

Nuclear grade

1.94

1.28–3.01

0.002

1.1

0.63–1.93

0.74

ER

0.21

0.11–0.44

<0.0001

0.29

0.12–0.72

0.0078

PgR

0.32

0.15–0.65

0.0017

   

Her2

1.26

0.47–2.87

0.63

   

Ki67 Labeling Index

2.3

0.96–6.82

0.063

   

Aurora A mRNA expression

2.54

1.25–5.25

0.010

2.3

1.10–4.92

0.027

Aurora A amplification

1.32

0.60–2.75

0.47

   

Aurora A protein expression

1.45

0.65–3.01

0.35

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