Table 3 Multivariate survival analysis (Cox regression model) including tumor stage and grade in PDAC

HR

95%CI

p-value

WHO stage

I

1

IIA

0.57

0.22-1.45

IIB

1.11

0.53-2.24

III

4.92

1.20-20.16

IV

1.88

0.56-6.33

0.029

Grade

G1/G2

1

G3

1.28

0.81-2.03

0.298

SIRT1-expression

low

1

high

1.65

1.01-2.69

0.045