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Table 1 The allele frequency distribution and results of logistic regression analysis (odds ratio OR and 95% confidence interval CI) of the studied RAD50 c.551+19G>A gene variant in controls and acute leukemia patients

From: Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia

   

Leukemia n=220

Controls n=504

OR [95 % CI]

p

Gene

Variant

Allele

ALL

AML

 

ALL

AML

ALL

AML

RAD50

c.551+19G>A

G

285

44

671

1a

1a

  

A

91

20

337

0.6358 [0.4854-0.8327]

0.9104 [0.5250-1.560]

0.00091

0.7194

   

ALL+AML

  

ALL+AML

RAD50

c.551+19G>A

G

329

671

1a

 
  

A

111

337

0.6718 [0.5222-0.8642]

0.00191

  1. aReference category.
  2. 1Result statistically significant (P<0.05), OR (95% CI) -Odds ratio (95% confidence interval).