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Table 1 Clinical profile of thyroid cancer patients and controls

From: Metallothionein 1G functions as a tumor suppressor in thyroid cancer through modulating the PI3K/Akt signaling pathway

Characteristics

     No. of patients (%)

 
 

PTC (n=178)

FTC (n=16)

MTC (n=9)

ATC (n=9)

Goiter (n=32)

Gender

     

   Male

48 (27.0)

3 (18.8)

4 (44.4)

4 (44.4)

2 (6.3)

   Female

130 (73.0)

13 (81.3)

5 (55.6)

5 (55.6)

30 (93.8)

Age (years, mean ± SD)

42.1 ± 15.3

49.5 ± 14.5

53.6 ± 9.5

65.6 ± 9.7

48.7 ±15.0

   ≤30

41 (23.0)

1 (6.3)

0 (0.0)

0 (0.0)

6 (18.8)

   30-50

92 (51.7)

7 (43.8)

4 (44.4)

1 (11.1)

9 (28.1)

   50-70

33 (18.5)

7 (43.8)

5 (55.6)

5 (55.6)

15 (46.9)

   >70

12 (6.7)

1 (6.3)

0 (0.0)

3 (33.3)

2 (6.3)

Tumor size (cm3)*

     

   ≤1

19 (14.8)

3 (42.9)

0 (0.0)

0 (0.0)

 

   1-3

34 (26.6)

1 (14.3)

0 (0.0)

1 (33.3)

 

   3-5

25 (19.5)

0 (0.0)

0 (0.0)

0 (0.0)

 

   >5

50 (39.1)

3 (42.9)

1 (11.1)

2 (66.7)

 

Tumor stage

     

   I

109 (61.2)

6 (37.5)

1 (11.1)

0 (0.0)

 

   II

25 (14.0)

3 (18.8)

2 (22.2)

0 (0.0)

 

   III

43 (24.2)

7 (43.8)

6 (66.7)

0 (0.0)

 

   IV

1 (0.6)

0 (0.0)

0 (0.0)

9 (100.0)

 

Invasion

     

   No

98 (55.1)

11 (68.8)

6 (66.7)

3 (33.3)

 

   Yes

80 (44.9)

5 (31.3)

3 (33.3)

6 (66.7)

 

Lymph node metastasis

     

   No

92 (51.7)

13 (81.3)

2 (22.2)

6 (66.7)

 

   Yes

86 (48.3)

3 (18.7)

7 (77.8)

3 (33.3)

 

Recurrence

     

   No

158 (88.8)

11 (68.8)

7 (77.8)

6 (88.9)

 

   Yes

20 (11.2)

5 (31.3)

2 (22.2)

3 (11.1)

 
  1. *Only 140 patients have the information of tumor size.