Figure 3

Paclitaxel resistant gene candidates in pooled samples. A) Candidate ‘hits’ identified in resistant pools of four cell lines. Genes found in multiple cell lines are color-coded and labeled. Dot surfaces and numbers within parentheses indicate insertion occurrence, and y-axis indicates total read numbers for each gene. B) Venn diagram showing candidate genes belonging to four cell lines. Only one gene (ABCB1) was shared by all four cell lines. C) Functional annotation analysis of pooled samples. Only genes with multiple hits were used in DAVID analysis. Only annotation groups with significant values (p-value<0.05, FDR<5%) are listed. The complete annotation chart and cluster chart are presented in the Additional file 4 Dataset S4.