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Table 3 Annual percent change (APC) with 95% confidence intervals (CIs) in premenopausal (< 50) and postmenopausal (≥ 50) breast cancer age standardized incidence rate (ASRs), estimated with the best-fitting joinpoint model

From: Higher incidence of premenopausal breast cancer in less developed countries; myth or truth?

Country

Postmenopausal (≥ 50)

Premenopausal (< 50)

Period

APC*(95% CI)

Period

APC*(95% CI)

Denmark

    
 

1975 – 1980

-1.23 (-4.00 to 1.63)

1975 – 2008

0.25 (0.05 to 0.46) **

 

1980 – 2008

2.01 (1.80 to 2.23) **

  

Sweden

    
 

1975 – 1979

3.00 (1.44 to 4.59) **

1975 – 2008

0.94 (0.79 to 1.10) **

 

1979 – 1985

-1.10 (-2.17 to -0.03 **

  
 

1985 – 1990

5.82 (4.22 to 7.45) **

  
 

1990 – 1993

-2.36 (-6.96 to 2.47)

  
 

1993 – 2002

2.63 (2.09 to 3.17) **

  
 

2002 – 2008

-1.30 (-2.10 to -0.49) **

  

Finland

    
 

1975 – 1984

2.32 (1.51 to 3.13) **

1975 – 1998

2.48 (2.18 to 2.77) **

 

1984 – 1988

6.26 (1.75 to 10.96) **

1998 – 2008

-1.20 (-2.19 to -0.19) **

 

1988 – 2008

2.24 (2.00 to 2.84) **

  

Norway

    
 

1975 – 2003

0.62 (0.30 to 0.94) **

1975 – 2008

0.96 (0.77 to 1.16) **

 

1993 – 1997

8.08 (2.83 to 13.60) **

  
 

1997 – 2003

2.24 (-0.01 to 4.55)

  
 

2003 – 2008

-2.21 (-4.37 to -0.01) **

  

US (whites)

    
 

1975 – 1982

0.89 (0.15 to 1.64) **

1975 – 1980

-1.09 (-2.48 to 0.32)

 

1982 – 1987

5.54 (3.70 to 7.41) **

1980 – 1986

2.63 (1.18 to 4.09) **

 

1987 – 1993

-0.27 (-1.50 to 0.98)

1986 – 2008

-0.07 (-0.22 to 0.08)

 

1993 – 2000

1.69 (0.74 to 2.65) **

  
 

2000 – 2004

-3.79 (-6.42 to -1.08) **

  
 

2004 – 2008

-0.17 (-1.91 to 1.60)

  

US (blacks)

    
 

1975 – 1978

-2.65 (-9.10 to 4.26)

1975 – 1991

1.32 (0.72 to 1.92) **

 

1978 – 1986

4.64 (2.74 to 6.58) **

1991 – 2008

-0.43 (-0.97 to 0.12)

 

1986 – 2008

0.67 (0.34 to 1.00) **

  
  1. *The model was specified to include a maximum of six joinpoits. The model constrained the joinpoints to be at least five years from each other (to be more conservative) and from the boundaries of the total study period.
  2. **Statistically significant annual percent changes are printed in bold.