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Table 2 Univariate and multivariate survival analyses by pN stage in patients with pT1 stage CC

From: Solitary lymph node metastasis is a distinct subset of colon cancer associated with good survival: a retrospective study of surveillance, epidemiology, and end-results population-based data

 

Univariate analysis

Multivariate analysis

Variable

5-year CCS

Log rank χ 2test

P

HR (95% CI)

P

Years of diagnosis

 

15.944

<0.001

 

<0.001

 1988-1993

94.9%

  

Reference

 

 1994-1999

95.6%

  

0.815 (0.784-0.848)

 

 2000-2003

96.6%

  

0.692 (0.667-0.718)

 

Sex

 

0.706

0.401

 

NI

 Male

96.0%

    

 Female

96.2%

    

Age

 

45.295

<0.001

 

<0.001

 <60

97.6%

  

Reference

 

 ≥60

95.3%

  

1.467 (1.419-1.516)

 

Race

 

16.447

<0.001

 

<0.001

 White

96.3%

  

Reference

 

 Black

93.4%

  

1.428 (1.152-1.770)

 

 Othera

97.6%

  

0.718 (0.528-0.976)

 

Grade

 

19.124

<0.001

 

<0.001

 High/moderate

96.2%

  

Reference

 

 Poor/anaplastic

93.1%

  

1.281 (1.234-1.330)

 

 Unknown

96.8%

  

0.871 (0.802-0.946)

 

Histotype

 

0.923

0.337

 

NI

 Adenocarcinoma

96.1%

    

Mucinous/signet ring cell

96.8%

    

No. of LNs dissected

 

0.413

0.520

 

NI

 <12

95.9%

    

 ≥12

96.5%

    

LNs status

 

221.646

<0.001

 

<0.001

 N0 (pI)

96.7%

  

0.456 (0.439-0.473)

 

 N1a

92.6%

  

Reference

 

 N1b

83.2%

  

1.424 (1.365-1.486)

 
  1. aOther includes American Indian/Alaska native, Asian/Pacific Islander, and unknown.
  2. NI: not included in multivariate survival analyses.