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Table 2 Clinical response to everolimus

From: Phosphorylation of mTOR and S6RP predicts the efficacy of everolimus in patients with metastatic renal cell carcinoma

Outcomes

Patients with tissue samples no. (%)

Patients without tissue samples no. (%)*

CR

0 (%)

0 (0%)

PR

1 (5.6%)

0 (0%)

SD ≥ 6 months

9 (50.0%)

3 (60.0%)

SD < 6 months

6 (33.3%)

0 (0%)

PD

2 (11.1%)

2 (40.0%)

ORR

1 (5.6%)

0 (0%)

CBR (CR + PR + SD ≥ 6 months)

10 (55.6%)

3 (60.0%)

DCR (CR + PR + SD)

16 (88.9%)

3 (60.0%)

PFS (months)

8.4 (95% CI: 2.163 - 14.637)

8.6 (95% CI: 1.909 - 15.291)

  1. *Two patients of this group were unavailable for clinical evaluation.
  2. Abbreviations: CBR clinical benefit rate, CI confidence interval, DCR disease control rate, ORR overall response rate, PFS progression-free survival.