Skip to main content
Figure 4 | BMC Cancer

Figure 4

From: Cell proliferation and apoptosis in rat mammary glands following combinational exposure to bisphenol A and genistein

Figure 4

Protein expressions in PND50 rats. Western blot analysis of cleaved Caspase-3, cleaved Caspase-9, pro-PARP, cleaved PARP, p-Bad and p21 protein expression in mammary glands of PND50 rats exposed prepubertally via lactating dams treated with BPA or/and genistein and SO. (A) Top panel depicts the Western blots of mammary gland proteins from SO (lanes 1, 5, 9, 13, 17 and 21), BPA (lanes 2, 6, 10, 14, 18 and 22), genistein (lanes 3, 7, 11, 15, 19 and 23) and BPA plus genistein (lanes 4, 8, 12, 16, 20 and 24) -treated groups with the appropriate antibodies shown on the left. For each treatment group, n = 6. (B) Densitometric values of Western blots from PND50 rats were reported as a percentage of the controls ± SEM: *p ≤ 0.05 compared with controls; **p ≤ 0.05 compared with BPA; and ***p ≤ 0.01 compared with genistein. No significant difference was detected for the house keeping protein GAPDH.

Back to article page