From: Atypical glandular cells in conventional cervical smears: Incidence and follow-up
Class | Cytological description | Recommendation |
---|---|---|
I | Normal cells | / |
II | Regenerative cells, immature metaplastic cells, important degenerative or inflammatory changes, para- and hyperkeratinizing cells. Normal endometrial cells even after the menopause. | cytological control if necessary (with or without anti-inflammatory or hormonal treatment) |
III | Important degenerative, iatrogenic or inflammatory changes of the cells where benignity or malignancy cannot be diagnosed with certainty even if the smear is adequately prepared. | short-term cytological control if necessary after anti-inflammatory or hormonal treatment, or immediate histological control |
IIID | Mild to moderate dysplasia (CIN I and II) | cytological control in 3 months |
IIIG | Abnormal cells of the glandular epithelium whose carcinomatous nature cannot be excluded with certainty; if possible with an indication of the endometrial, endocervical or extra-uterine origin of the cells. | cytological or histological control |
IV a | Severe dysplasia or carcinoma in situ (CIN III) | histological control |
IV b | Severe dysplasia or carcinoma in situ; invasive carcinoma not excluded | histological control |
V | Invasive epidermoid carcinoma of the uterine cervix; adenocarcinoma, indicating if possible the endometrial, endocervical or extra-uterine origin of the cells. Other malignant tumours. | histological control |