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Table 1 Summary of 20 genes examined by methylation analysis

From: The 5'-end transitional CpGs between the CpG islands and retroelements are hypomethylated in association with loss of heterozygosity in gastric cancers

Gene symbol

Synonym

Gene description

Accession no.

CpG islands

   CDH1

E-CADHERIN

Cadherin 1, type 1, E-cadherin (epithelial)

NM_004360

   RABGEF1

AJ250042

RAB guanine nucleotide exchange factor (GEF) 1

NM_014504

   STAG1

SA1

Stromal antigen 1

NM_005862

   MYBPC2

AJ250042

Myosin binding protein C, fast type

NM_004533

   VDR

J03258

Vitamin D (1,25- dihydroxyvitamin D3) receptor

NM_000376

   ESR2

AF051428

Estrogen receptor 2 (ER beta)

NM_001437

   MLH1

HMLH1

MutL homolog 1, colon cancer, nonpolyposis type 2

NM_000249

   FLJ43855

AK125843

similar to sodium- and chloride-dependent creatine transporter

NM_198857

   PTEN

BZS

Phosphatase and tensin homolog

NM_000314

   CDKN2A

P16

Cyclin-dependent kinase inhibitor 2A

NM_000077

   PAX5

AY463952

Paired box gene 5 (B-cell lineage specific activator)

NM_016734

   RUNX2

CBFA1

Runt-related transcription factor 2

NM_004348

   RUNX3

CBFA3

Runt-related transcription factor 3

NM_004350

   KIAA1752

 

Homo sapiens mRNA for KIAA1752 protein

AB051539*

   MUC8

 

Mucin 8, tracheobronchial

U14383*

Non-island CpGs

   MAGEA2

MAGE-A2

Melanoma antigen family A, 2

NM_005361

   DDX53

CAGE

DEAD (Asp-Glu-Ala-Asp) box polypeptide 53

NM_182699

   TFF2

SML1

Trefoil factor 2 (spasmolytic protein 1)

NM_005423

   SERPINB5

MASPIN

Serpin peptidase inhibitor, clade B (ovalbumin), member 5

NM_002639

   MSLN

MPF

Mesothelin isoform 2 precursor

NM_013404

  1. *GenBank accession number.