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Table 5 Diagnostic sensitivities for the different imaging modalities for the 36 screen-detected BC

From: Breast cancer screening in women at increased risk according to different family histories: an update of the Modena Study Group experience

 

Mx

US

Mx+US

MRI*

 

Sensitivity**

 

Sensitivity**

 

Sensitivity**

 

Sensitivity**

 
 

(%)

TP/TP+FN

(%)

TP/TP+FN

(%)

TP/TP+FN

(%)

TP/TP+FN

All women

78

28/36

50

18/36

97

35/36

100

4/4

< 50 years

64

7/11

64

7/11

100

11/11

  

≥ 50 years

84

21/25

44

11/25

96

24/25

100

4/4

BRCA+

50

2/4

75

3/4

75

3/4

100

4/4

High risk

90

19/21

52

11/21

100

21/21

  

Intermediate risk

50

4/8

50

4/8

100

8/8

  

Slightly increased risk

100

3/3

0

0/3

100

3/3

  
  1. Note.- Mx = Mammography; US = Ultrasonography; MRI = Magnetic resonance imaging
  2. * MRI was performed only in women who were BRCA carriers
  3. ** Sensitivity was defined as the percentage of cancers detected (with a specific modality) among all cancers detected with any modality: TP/(TP+FN) where TP is true-positive and FN is false-negative