Table 5 Correlation between the amplification and molecular breast subtypes.
Region of amplification | Basal | Non Basal | p-value | ERBB2 | Non ERBB2 | p-value | Luminal A | Non Luminal A | p-value |
|---|---|---|---|---|---|---|---|---|---|
| Â | No. of patients (%) | Â | No. of patients (%) | Â | No. of patients (%) | Â | |||
11q13 | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Amplification | 1 (5.5) | 22 (45.8) | p = 0.006 | 2 (25) | 21 (36.2) | NS | 19 (57.6) | 4 (12.1) | p = 0.0003 |
No Amplification | 17 (94.5) | 26 (54.2) | Â | 6 (75) | 37 (63.8) | Â | 14 (42.4) | 29 (87.9) | Â |
12p13 | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Amplification | 5 (27.8) | 2 (4.2) | p = 0.02 | 1 (11.1) | 6 (10.5) | NS | 1 (3.1) | 6 (17.6) | NS |
No Amplification | 13 (72.2) | 46 (95.8) | Â | 8 (88.9) | 51 (89.5) | Â | 31 (96.9) | 28 (82.4) | Â |
17q12 | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Amplification | 0 (0) | 6 (17.6) | NS | 5 (71.4) | 1 (2.2) | p = 2.061e-06 | 0 (0) | 6 (20) | NS |
No Amplification | 19 (100) | 28 (82.4) | Â | 2 (28.6) | 45 (97.8) | Â | 23 (100) | 24 (80) | p = 0.065 |