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Figure 2 | BMC Cancer

Figure 2

From: Expression analysis of mammaglobin A (SCGB2A2) and lipophilin B (SCGB1D2) in more than 300 human tumors and matching normal tissues reveals their co-expression in gynecologic malignancies

Figure 2

Mammaglobin A and lipophilin B (co)expression in breast and gynecologic tumors and matched normal samples. Expression profiles were determined using two different Clontech cancer profiling arrays for each gene (see Methods). Mammaglobin A and lipophilin B expression were each analyzed in 59 matched breast tumor/normal samples (Figures 2A and 2B), 49 matched uterine (Figures 2C and 2D), 18 matched ovarian (Figures 2E and 2F), two matched samples from the uterine cervix (Figures 2G and 2H), as well as in nine further tumor entities (data not shown). Rows N represent normal tissue, and rows T represent tumor. The outlined groups of three dots represent normal tissue (breast N: -G, -I, -K, uterus N: -V, -Z, and ovary N: -I, -K), primary tumor (breast T: -G, -I, -K, uterus T: -V, -Z, and ovary T: -I, -K), and metastases (breast T: -H, -J, -L, uterus T: -W, -AA, and ovary T: -J, -L) from the same patient. Control dots (labeled MG and LipB, respectively) were co-hybridized in order to confirm the specificity of mammaglobin A and lipophilin B probes (see results).

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