Figure 3From: Null mutation for Macrophage Migration Inhibitory Factor (MIF) is associated with less aggressive bladder cancer in miceBladder cancer specimens from MIF WT (A, B) and KO (C, D) animals treated with BBN. A and C are representative areas of tumor with (A) and without (C) muscle invasion. B and D show immunohistochemical staining for vascular structures (arrowheads) by PECAM-1 in the same region. Note the marked increase in number of vessels in the WT animal (B) as compared to the KO (D).Back to article page