Table 5 Outcomes of the brain metastases from breast cancer treatment according to treatment modality, number of patients, median survival and prognostic factors by other researches.
Authors | Patients(n) | Treatment | Median OS(mo) | Prognostic factors (univarate analysis) |
|---|---|---|---|---|
Firlik et al. (21),2000 | 58 | SRS | 13 | --- |
Pieper et al.(22),1997 | 63 | Surgery+- WBRT | 16 | Age, menopausal status, postoperative RT, KPS, systemic disease |
Wronski et al. (23), 1996. | 70 | Surgery+- WBRT | 14 | Positive estrogen receptor, meningeal carcinomatosis |
Lentzsch et al. (24), 1999 | 145 | WBRT | 6.1 | KPS, dose of RT, No. of BM, grade of primary |
Mizutani et al. (19), 2001 | 113 | WBRT | 4.0 | KPS, No. of BM, systemic metastases without bony metastasis |
Fokstuen et al. (20), 2000 | 99 | WBRT | 5.0 | No. of BM, systemic metastases |
Mahmoud-Ahmed et al. (25) 2002 | 116 | WBRT | 4.1 | KPS, WBRT dose, RPA class |
Present study. 2006 | 174 | Surgery +WBRT or WBRT | 6.4 | KPS, RPA, single BM, resection of lesion, extracranial metastase, control primary tumor, BS-BM system |