Figure 2
From: Expression profile of CREB knockdown in myeloid leukemia cells
A network depicting interactions between direct CREB targets (shown in grey) and proteins that these interact with (shown in white). PTGS2, NR4A3 and TOM1 are direct CREB targets whose regulation by CREB was previously described in the literature (clue lines). PTGS2 (COX2) emerges as a central player in this network, and is thus implicated as a potential regulator of leukemias.