Table 3 Comparision of clinicopathological features of patients and immunohistochemical results of biomarkers between the low SUV group and the high SUV group in 47 cases of node-negative breast cancer
Parameters | High SUV group (n = 27) | Low SUV group (n = 20) | p-value | |
|---|---|---|---|---|
SUV | Ave± SD | 7.8± 3.4 | 2.2± 1.0 | <0.0001 |
Age | Ave± SD | 55.6± 10.1 | 53.2± 10.0 | 0.42 |
Tumor size | Ave± SD | 3.1± 2.1 | 2.4± 2.9 | 0.33 |
Nuclear grade | 1 and 2 | 8 | 15 | 0.004 |
3 | 19 | 5 | ||
ER | <10% | 11 | 3 | 0.06 |
10% ≦ | 16 | 17 | ||
HER2 | 0,1+,2+ (FISH-) | 20 | 18 | 0.17 |
3+ or FISH+ | 7 | 2 | ||
CENP-F | Positive | 20 | 9 | 0.04 |
Negative | 7 | 11 | ||
n-CDC6 | Positive | 13 | 10 | 0.9 |
Negative | 10 | 10 | ||
c-CDC6 | Positive | 9 | 7 | 0.9 |
Negative | 18 | 13 | ||
Ki67 | Positive | 25 | 12 | 0.02 |
Negative | 2 | 8 | ||
p53 | Positive | 9 | 2 | 0.06 |
Negative | 18 | 18 | ||
Molecular subtypes | Luminal A | 16 | 17 | 0.05 |
HER2 | 7 | 2 | ||
Triple negative | 4 | 1 |