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Table 1 Correlation of clinicopathologic parameters with VEGF-C and COX-2 expressions.

From: Coexpression of VEGF-C and COX-2 and its association with lymphangiogenesis in human breast cancer

  

VEGF-C Expression

 

COX-2 Expression

 

Factor

No. of cases

Low

High

P value

Low

High

P value

LVD

 

9.63 ± 5.09

12.83 ± 5.27

0.007a

9.17 ± 5.07

11.96 ± 5.32

0.012a

Age

       

   ≤ 50

40

23

17

0.944

12

28

0.383

   > 50

30

17

13

 

12

18

 

Tumor size

       

   ≤ 2

28

18

10

0.324

10

18

0.837

   > 2

42

22

20

 

14

28

 

Hisyological grade

       

   G1 and G2

41

31

10

< 0.001

17

24

0.132

   G3

29

9

20

 

7

22

 

Lymph node metastasis

       

   Positive

32

13

19

0.010

6

26

0.012

   Negative

38

27

11

 

18

20

 

Histology

       

   IDS, NOS

59

32

27

0.420

19

40

0.614

   Others

11

8

3

 

5

6

 

ER

       

   Positive

54

32

22

0.511

22

32

0.037

   Negative

16

8

8

 

2

14

 

PR

       

   Positive

46

27

19

0.716

19

27

0.087

   Negative

24

13

11

 

5

19

 

c-erbB-2

       

   Positive

13

6

7

0.375

2

11

0.205

   Negative

57

34

23

 

22

35

 

LVI

       

   Positive

25

10

15

0.031

4

21

0.016

   Negative

45

30

15

 

20

25

 
  1. a Analysis by Mann-Whitney U test.