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Table 4 Association of polymorphisms in TOP3A and BLM and risk of cancer (all cancer cases and all controls combined).a

From: Association between polymorphisms in RMI1, TOP3A, and BLM and risk of cancer, a case-control study

SNP

Genotype

OR

95% CI

FPRP 0.1b

FPRP 0.01

rs1563634c

AA

1.0

-

-

 

(TOP3A)

AG

1.7

1.1–2.6

0.48

0.92

 

GG

1.8

1.1–2.8

0.29

0.84

rs12945597

GG

1.0

-

-

-

(TOP3A)

AG

1.5

1.1–1.9

0.014

0.13

 

AA

1.6

1.0–2.5

0.36

0.89

rs401549

AA

1.0

-

-

-

(BLM)

AG

1.2

0.89–1.5

-

-

 

GG

1.3

0.82–2.2

-

-

rs2532105

CC

1.0

-

-

-

(BLM)

CT+TT

1.8

1.5–2.5

0.029

0.27

  1. a Statistically significant associations (p ≤ 0.05) are denoted in bold. The analyses were adjusted for age and sex.
  2. b FPRP is only calculated for significant p-values.
  3. c For rs1563634, the reference category was changed to the variant allele in order to display cancer risk increment.