Figure 1From: Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells Effects of AEE788 (1a) or RAD001 (1b) on kidney cancer proliferation in vitro. A498, Caki-1 or KTC-26 cells were treated with various concentrations of AEE788 or RAD001, or remained untreated (control). Cell proliferation was then assessed using the MTT dye reduction assay. Cell numbers at day 2 and 3 (48 h and 72 h) were compared to the number on day 1 (24 h, as 100%). One representative of 6 experiments is shown. * indicates significant difference to controls (p < 0.05). SDintraassay < 15%.Back to article page