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Table 1 Association between HIF-1α and clinicopathological factors

From: Expression of HIF-1alpha and VEGF in colorectal cancer: association with clinical outcomes and prognostic implications

Factors

No. of patients

HIF-1α

 
  

Positive expression

χ2

P

Age

    

<60

24

15(62.5%)

0.839

0.363

≥ 60

47

24(51.1%)

  

Sex

    

Male

43

24(55.8%)

0.034

0.853

Female

28

15(53.6%)

  

Tumor size

    

<5 cm

31

17(54.8%)

0.000

0.989

≥ 5 cm

40

22(55%)

  

Differentiation

grade

    

Poor

11

4(36.4%)

2.233

0.327

Moderate

48

27(56.3%)

  

Well

12

8(66.7%)

  

Invasion Depth

    

T1 + T2

10

6(60%)

0.121

0.728

T3 + T4

61

33(54.1%)

  

Tumor stage

    

I+II

42

15(35.7%)

15.336

<0.001

III+IV

29

24(82.8%)

  

lymphnode matastasis,

    

No

44

17(38.6%)

12.007

<0.001

Yes

27

22(81.5%)

  

liver matastasis

    

NO

60

29(48.3%)

6.806

0.009

Yes

11

10(90.1%)

  
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