Table 4 Detection sensitivity for SMARCB1 mutations in mosaic mixes of tumor DNA
From: Rapid detection of SMARCB1 sequence variation using high resolution melting
Exon | Tumor | Mutation | Proportion of tumor DNA: normal DNA |
|---|---|---|---|
Exon 2 | 3180 | c157C>T | 1:4 |
Exon 5 | 3180 | c569-570ins18 | 1:4 |
Exon 3 | 1993 | c325insG | 1:4 |
Exon 5 | 3161 | c601C>T | 1:10 |
Exon 9 | 3388 | c1148delC | 1:1000 |
Exon 6 | 3161 | c795+2delinsATGA | 1:1000 |