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Table 1 Cell viabilities of Compound K in various cancer cell lines in vitro

From: Compound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells

Cell lines

IC50 (μM)a

HL-60

14.1

U937

16.5

HeLa

29.9

A549

37.9

HepG2

59.4

P388

18.4

A431

37.9

  1. aIC50 is defined as the concentration that results in a 50% decrease in the number of cells compared to that of the control cultures in the absence of Compound K. The values represent the means of results from three independent experiments with similar patterns.
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BMC Cancer

ISSN: 1471-2407

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