Table 2 Unclassified variants identified among fifty-four triple-negative cases:
From: The prevalence of BRCA1 mutations among young women with triple-negative breast cancer
Gene | Exon | Mutation | Designation | Mutation Type | Age of Onset | Ethnic Group |
|---|---|---|---|---|---|---|
BRCA1 | 22 | 676C>A | S186Y | Missense | 36 | Puerto Rican |
BRCA1 | 16 | 4956A>G | S1613G | Missense | 40 | African American |
BRCA1 | 15 | 4654G>T | S1512I | Missense | 36 | Caucasian |
BRCA1 | 11 | 1186A>G | Q356R | Missense | 40 | Iranian |