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Table 6 Odds ratios for association between cotton and wool dust ever exposure and lung cancer in two studies in Montreal, stratified by smoking status

From: Lack of a protective effect of cotton dust on risk of lung cancer: evidence from two population-based case-control studies

Exposure group

Study 1

Study 2

Pooled

 

Population controls

Cancer controls

All controls, weighted

Males

Females

Population controls

na

ORb(95% CI)

OR (95% CI)

OR (95% CI)

n

OR (95% CI)

n

OR (95% CI)

n

OR (95% CI)

Cotton dust

          

 All subjects

66

1.4 (0.9-2.3)

1.0 (0.7-1.4)

1.2 (0.8-1.7)

108

1.4 (1.0-2.0)

131

1.0 (0.7-1.5)

305

1.2 (1.0-1.5)

 Never/Low smokersc

8

0.7 (0.3-2.0)

0.7 (0.3-1.6)

0.7 (0.3-1.6)

15

2.1 (1.1-4.2)

12

0.9 (0.4-1.9)

37

1.0 (0.7-1.6)

 Medium/High Smokersc

58

2.1 (1.1-4.0)

1.1 (0.7-1.6)

1.4 (0.9-2.2)

91

1.3 (0.8-1.8)

119

1.0 (0.6-1.6)

266

1.3 (1.0-1.7)

Wool dust

          

 All subjects

42

1.2 (0.7-2.3)

0.8 (0.5-1.3)

1.0 (0.6-1.6)

46

0.9 (0.6-1.4)

47

1.2 (0.7-2.0)

135

1.0 (0.8-1.4)

 Never/Low smokersc

4

1.0 (0.3-3.3)

0.6 (0.2-1.8)

0.7 (0.2-2.1)

5

1.1 (0.4-3.0)

6

1.2 (0.4-3.1)

15

0.9 (0.5-1.7)

 Medium/HighSmokersc

38

1.5 (0.7-3.2)

0.9 (0.6-1.4)

1.1 (0.6-1.9)

40

0.9 (0.5-1.4)

41

1.2 (0.6-2.4)

119

1.0 (0.7-1.5)

  1. a n = number of exposed cases.
  2. b OR refers to odds ratio, adjusted for: age, ethnicity (French Canadian or other), years of education (0-7, 8-12 or 13+), familial financial situation during childhood (difficult, intermediate or comfortable), proxy respondent (yes or no), cumulative smoking index (CSI), and any occupational exposure to asbestos, chromium, nickel or silica. Pooled results are additionally adjusted for study.
  3. c Low smokers are defined as those having a CSI value ≤25% percentile of CSI values among ever smoker.