Figure 3From: Aurora kinase B is important for antiestrogen resistant cell growth and a potential biomarker for tamoxifen resistant breast cancerBarasertib inhibits expression of Aurora kinase B and phosphorylation of INCENP. Western blots showing protein expression of Aurora kinase B, INCENP and phosphorylated INCENP (p-INCENP) in lysates from parental (T47D) and fulvestrant resistant (182R-1 and 182R-2) cells treated with barasertib (50 nM) or DMSO (control) for the indicated time periods (4–96 hours). Heat shock protein 70 (Hsp70) was used as loading control.Back to article page