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Figure 3 | BMC Cancer

Figure 3

From: The involvement of insulin-like growth factor 2 binding protein 3 (IMP3) in pancreatic cancer cell migration, invasion, and adhesion

Figure 3

IMP3 regulates CD44 and KIF11. (A) Total CD44 protein was measured in whole cell lysates 48 h after transfection. Treatment with IMP3 siRNA resulted in a significant decrease in CD44 protein relative to scrambled siRNA-treated controls. Inset Representative blots of CD44 and corresponding β-actin. *P < 0.05 relative to scrambled siRNA-transfected controls. (B) Levels of KIF11 and KIF14 mRNA were measured 48 h after siRNA transfection and expressed in amount of fold-change relative to scrambled siRNA-treated controls. *P < 0.05 relative to scrambled siRNA-transfected controls.

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