Table 4 Association between breast density/parenchymal pattern and breast cancer

BI-RADS

Reader 1

D1

29

103

22.0

1.00 (reference)

-

D2

25

72

25.8

1.25 (0.67-2.31)

0.482 (NS)

D3

42

62

40.4

2.47 (1.39-4.39)

0.002

D4

26

25

51.0

3.87 (1.91-7.85)

<0.001

D1+D2

54

175

23.6

1.00 (reference)

-

D3+D4

68

87

43.9

2.58 (1.64-4.04)

<0.001

Reader 2

D1

32

114

21.9

1.00 (reference)

-

D2

39

90

30.2

1.57 (0.91-2.72)

0.106 (NS)

D3

38

44

46.3

3.17 (1.74-5.76)

<0.001

D4

13

14

48.1

3.45 (1.45-8.25)

0.005

D1+D2

71

204

25.8

1.00 (reference)

-

D3+D4

51

58

46.8

2.56 (1.59-4.10)

<0.001

Tabár

Reader 1

PI

34

92

27.0

1.56 (0.83-2.92)

0.168 (NS)

PII

20

85

19.0

1.00 (reference)

-

PIII

5

9

35.7

2.36 (0.71-7.81)

0.160 (NS)

PIV

59

60

49.6

4.14 (2.26-7.61)

<0.001

PV

4

16

20.0

1.04 (0.31-3.48)

0.955 (NS)

PI+PII+PIII

59

186

24.1

1.00 (reference)

-

PIV+PV

63

76

45.3

2.61 (1.67-4.07)

<0.001

Reader 2

PI

49

111

30.6

3.31 (1.58-6.95)

0.002

PII

10

75

11.8

1 (reference)

-

PIII

6

8

42.9

5.62 (1.61-19.62)

0.007

PIV

43

42

50.6

7.69 (3.49-16.91)

<0.001

PV

14

26

35.0

4.05 (1.59-10.30)

0.003

PI+PII+PIII

65

194

25.1

1.00 (reference)

-

PIV+PV

57

68

45.6

2.51 (1.59-3.97)

<0.001

Percentage density

Reader 1**

Q1

40

122

24.7

1 (reference)

-

Q2

36

76

32.1

1.45 (0.85-2.49)

0.173 (NS)

Q3

32

44

42.1

2.24 (1.24-4.02)

0.007

Q4

14

20

41.2

2.17 (0.98-4.81)

0.056 (NS)

Q1+Q2

76

198

27.7

1.00 (reference)

-

Q3+Q4

46

64

41.8

1.87 (1.17-3.00)

0.009

Reader 2**

Q1

28

95

22.8

1 (reference)

-

Q2

45

99

31.3

1.55 (0.89-2.68)

0.120 (NS)

Q3

33

56

37.1

2.03 (1.10-3.74)

0.023

Q4

16

12

57.1

4.65 (1.93-11.16)

0.001

Q1+Q2

73

194

27.3

1.00 (reference)

-

Q3+Q4

49

68

41.9

1.92 (1.21-3.07)

0.006