Skip to main content
Figure 1 | BMC Cancer

Figure 1

From: Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts

Figure 1

B16F10 melanoma lung metastasis inShb+/+, +/− and −/− mice. (A) Pictures show examples of lungs without (+/+) and with (+/−) B16F10 melanoma metastases. (B) At time of sacrifice, numbers of lung metastases were determined (arrow indicates a metastasis). These are given as absolute numbers for each mouse (B) or scored as relative frequencies after grouping in categories (C) (0 = 0, 1 = 1–5, 2= >5). Means ± SEM for n = 16 +/+, n = 16 +/−, n = 11 +/+ F4 and n = 11 −/− F4. * and ** indicate p < 0.05 and p < 0.01, respectively when compared with corresponding +/+ controls by Mann–Whitney U test.

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us