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Table 1 Baseline characteristics

From: Everolimus in metastatic renal cell carcinoma after failure of initial anti–VEGF therapy: final results of a noninterventional study

Characteristics

Total population (N = 334)

Age, median (range), y

68 (22–89)

Sex, n (%)

  Men

250 (75)

  Women

84 (25)

Tumor histology, n (%)

 

  Clear cell

293 (88)

  Non–clear cell

24 (7)

  Missing

17 (5)

KPS, median (range)

80 (50–100)

Time since diagnosis, median (range), y

 

  Initial

3.3 (0–34)

  Metastasis

1.7 (0–16)

MSKCC risk status at start of first-line therapy, n (%)a

  Favorable

84 (35)

  Intermediate

134 (56)

  Poor

20 (8)

Primary metastatic site, n (%)b

  Lung

226 (68)

  Lymph node

145 (43)

  Skeletal system

125 (37)

  Liver

87 (26)

  Adrenal gland

47 (14)

Previous surgery, n (%)

325 (97)

  Previous nephrectomy

300 (90)

Number of previous antineoplastic therapies, n (%)

  1

240 (72)

  2

69 (21)

  ≥3

25 (7)

  1. Abbreviations: MSKCC, Memorial Sloan-Kettering Cancer Center; KPS, Karnofsky performance status.
  2. a100% relate to patients with documented evaluation (n = 238).
  3. bPatients could have had multiple metastatic locations.